Professor Paul Fine

Paul Fine's has broad interests in infectious disease epidemiology, with particular emphasis upon vaccines (trials, safety and efficacy evaluations of BCG, measles, pertussis, mumps, polio), mycobacterial diseases (including genetics, immune responses, risk factors, vaccine and drug trials of leprosy and tuberculosis) and family studies (in the broadest sense, including both Mendelian and non-Mendelian inheritance).

He directed a large study of tuberculosis, leprosy and HIV in northern Malawi (the Karonga Prevention Study - see http://www.lshtm.ac.uk/ideu/kps ) from 1978 to 2006.

He directed a large epidemiological research programme (the "Karonga Prevention Study") in Malawi from 1978-2006, concentrating at first upon leprosy, then tuberculosis, and ultimately HIV, and including demographic surveillance, vaccine evaluation, and studies of other infections in a rural population in northern Malawi.

Since 1997 he has worked on a wide variety of vaccine issues, including the evaluation of non-specific effects of vaccines, methods for field evaluation of veterinary vaccines, the implications of the transmissibility of oral polio vaccine viruses for the polio eradication initiative, and methods for optimising vaccination schedules.